Everything about Conolidine alkaloid for chronic pain
Most a short while ago, it has been discovered that conolidine and the above derivatives act within the atypical chemokine receptor 3 (ACKR3. Expressed in equivalent areas as classical opioid receptors, it binds to a big range of endogenous opioids. Contrary to most opioid receptors, this receptor acts for a scavenger and doesn't activate a 2nd mes